Deforestation and climate change are destabilizing the Amazon — the world’s largest rainforest, which is home to one in ten known species. Estimates of where an Amazon tipping point could lie range from 40% deforestation to just 20% forest-cover loss8. About 17% has been lost since 1970. The rate of deforestation varies with changes in policy. Finding the tipping point requires models that include deforestation and climate change as interacting drivers, and that incorporate fire and climate feedbacks as interacting tipping mechanisms across scales.