As there are trillions of images assaulting your audience, competing for their attention, the least you can do is not have the words and images in your design competing with each other. Take a statement like, “we cure cancer for one dollar.” It isn’t necessary to make those words look interesting. They are interesting. If you try to make interesting words look interesting, the way they look competes with their meaning. Also. if you want to draw attention to an interesting image, the words that accompany it shouldn’t be unusual.